Table 3.

Mean weight change after treatment by subgroup

Subgroup	Weight change		P value	95% CI
	(lbs)	(%)*
All patients (n = 317)†	−17.8 (SD = 21.1)	−7.6 (SD = 7.8)
Patients prescribed medication at weight plateau (n = 68, 21.5%)‡	−15.8 (SD = 27.8)	−6.9 (SD = 8.8)	.3901§	(−20.1, −15.4)
Patients prescribed medication at weight regain (n = 249, 78.5%)‡	−18.3 (SD = 19.0)	−7.7 (SD = 7.6)
Surgery type
Sleeve gastrectomy (n = 61)	−9.8 (SD = 13.5)	−4.3 (SD = 5.7)	.001§	(−20.1, −15.4)
Roux-en-Y gastric bypass (n = 256)	−19.7 (SD = 22.2)	−8.3 (SD = 8.1)
Patients who lost ≥5% total weight with treatment (n = 172, 54%)	−29.7 (SD = 21.9)	−12.6 (SD = 7.2)
Patients who lost ≥ 10% total weight with treatment (n = 96, 30.3%)	−40.7 (SD = 23.7)	−17.1 (SD = 6.7)
Patients who lost ≥ 15% total weight with treatment (n = 49, 15.4%)	−52.9 (SD = 27.7)	−22.02(SD = 6.2)

CI = confidence interval; SD = standard deviation.

^*Calculated this number as [(weight at nadir postmedications) – (weight at start of medication)]/ (weight at start of medication).

^†Missing data for 2 patients.

^‡Plateau defined as weight that is within 3% above or below nadir weight postoperatively before medication. If above 3% patient defined as starting medication at weight regain.

^§Two-sample t-test of means conducted for posttreatment weight change (lbs).