Table 4.
Medication | Number of patients (%) | Treatment period weight loss | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
≥5% | ≥10% | ≥15% | ||||||||
OR | P value | 95% CI | OR | P value | 95% CI | OR | P value | 95% CI | ||
Topiramate | 194 (60.8%) | 1.03 | .901 | (.65, 1.64) | 1.9 | .018 | (1.1, 3.2) | 2.08 | .041 | (1.03, 4.2) |
Phentermine | 121 (37.9%) | 1.18 | .504 | (.73, 1.89) | 1.09 | .729 | (.66, 1.82) | 1.42 | .27 | (.63, 1.77) |
Metformin | 123 (38.6) | 1.01 | .98 | (.63, 1.61) | 1.15 | .583 | (.70, 1.90) | .96 | .91 | (.51, 1.8) |
Bupropion | 75 (23.5%) | .92 | .776 | (.54, 1.58) | 1.1 | .753 | (.62, 1.93) | 1.23 | .55 | (.62, 2.46) |
Zonisamide | 65 (20.4%) | 1.15 | .643 | (.64, 2.04) | 1.03 | .914 | (.57, 1.89) | .97 | .94 | (.46, 2.07) |
CI = confidence interval; OR = odds ratio.
Model is adjusted for type of surgery and BMI at start of medications.