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. 2018 Mar 31;3(3):108–117. doi: 10.1016/j.ncrna.2018.03.001

Fig. 2.

Fig. 2

General mechanisms for lncRNA classification. A) lncRNAs can act as guides to target chromatin-modifying complexes to specific genomic locations for the regulation of gene expression. B) lncRNAs can act as dynamic scaffolds for cofactors to transiently assemble together. C) lncRNAs can bind to microRNAs or transcription factors as decoys to sequester them away from their targets, affecting transcription and translation.