Table 3.
Phenotypic and genotypic characteristics of 36 S. aureus isolates susceptible to vancomycin and resistant to teicoplanin (VSSA/TRSA)*
| ST1 | CC2 | SCC mec type3 | MICVAN4 (mg/L) | MICTEI5 (mg/L) | Presumable CLONE | No. of strains | Other resistance genes found (No. of strains) | Year of isolation (No. of strains) |
|---|---|---|---|---|---|---|---|---|
| ST247 | CC8 | IA | 1–2 | 4–8 | IBERIAN | 10 |
ermA (10), ermC (2), aacA-aphD (10), aadD (10) |
1994(8), 2003(1), 2005(1) |
| ST241 | CC8 | III | 1–2 | 4–16 | FINLAND-UK | 7 |
ermA (7), linA(1), aacA-aphD (7), aadD (4), aph(3″)-IIIa (6) |
2003(2), 2004(2), 2005(1), 2007(2) |
| ST239 | CC8 | III | 2 | 4–8 | BRASILIAN | 5 |
ermA (5), ermC (2), aacA-aphD (5), aph(3″)-IIIa (4) |
1991(1), 1994(4) |
| ST8 | CC8 | IV | 1–2 | 4 | UK EMRSA-2 | 4 |
ermA (1), ermC (1), aacA-aphD (1), aadD (2) |
2004(1), 2005(3) |
| ST254 | CC8 | IV | 2 | 4 | HANNOVER | 3 |
ermA (3), aph(3″)-IIIa (3) |
1994(2), 2005(1) |
| ST461 | CC5 | I | 2 | 4 | UD6 | 2 | ND7 | 1991(2) |
| ST2326 | CC5 | NT | 2 | 4 | UD6 | 2 |
ermC (2), aadD (2) |
1991(2) |
| ST5 | CC5 | I | 2 | 8 | UK EMRSA-3 | 1 | ND7 | 1991(1) |
| ST1 | CC1 | IV | 2 | 4 | UD6 | 1 | ND7 | 2005(1) |
| ST2323 | single | IA | 2 | 8 | UD6 | 1 |
ermA (1), aacA-aphD (1), aadD (1) |
1994(1) |
Legend: *According to EUCAST, 2018; 1ST Sequence type; 2CC Clonal complex; 3SCCmec type Staphylococcal chromosome cassettes mec type; 4VAN Vancomycin; 5TEI Teicoplanin; 6UD Undefined; 7ND Not detected