Table 2.

Association between number of anti-hypertensive medication and injurious falls (N = 210)

	Unadjusted OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Number of anti-hypertensive medication
0	1.00		1.00
1	0.92 (0.30–2.87)	0.89	2.10 (0.48–9.18)	0.33
≥ 2	4.75 (1.77–12.72)	< 0.01	5.45 (1.49–19.93)	0.01
Charlson comorbidity index	1.33 (1.14–1.56)	< 0.01	1.26 (1.04–1.54)	0.02
High risk of falla	5.69 (2.42–13.36)	< 0.01	7.21 (2.37–21.94)	< 0.01
Visual impairment	2.48 (1.01–6.08)	0.05	2.02 (0.70–5.86)	0.19
Exposure to psychotropic medication	2.21 (0.97–5.06)	0.06	1.12 (0.38–3.37)	0.83
Polypharmacy	2.22 (1.08–4.54)	0.03	1.29 (0.49–3.43)	0.61
Age (years)	0.92 (0.82–1.04)	0.19
BMI (kg/m2)	1.06 (0.98–1.13)	0.13
Chinesec	2.99 (0.62–14.34)	0.17
SBP on admission (mmHg)	1.01 (0.99–1.03)	0.13
DBP on admission (mmHg)	1.01 (0.98–1.04)	0.52
Hearing impairment	1.27 (0.41–3.92)	0.67
Use of walking aidb	8.18 (3.29–20.31)	< 0.01
Smoking history	1.06 (0.42–2.67)	0.90
Alcohol history	1.13 (0.34–3.74)	0.84
Medical history
Hypertension	1.05 (0.47–2.38)	0.90
Cerebrovascular accident or transient ischaemic attack	1.97 (0.87–4.49)	0.11
Ischaemic heart disease	1.26 (0.57–2.76)	0.56
Diabetes mellitus	1.17 (0.60–2.28)	0.65
Hyperlipidaemia	0.91 (0.44–1.89)	0.81
Osteoporosis	1.05 (0.33–3.32)	0.93
Cancer	1.28 (0.48–3.46)	0.62
Cognitive impairment	1.33 (0.47–3.80)	0.59
Prior history of fallsb	2.51 (1.18–5.37)	0.02
Statin use	0.88 (0.45–1.71)	0.71

OR Odds ratio, CI 95% confidence interval, SBP Systolic blood pressure, DBP Diastolic blood pressure

^aHigh risk of fall = Defined using Morse Fall Scale risk score of 55 or more; Polypharmacy = Use of 4 or more chronic medication

^bEven though these variables had p < 0.10 in univariate analysis, they were not included in the multivariate analysis as these variables were part of the high fall risk, which we had already adjusted for

Reference group:

^cNon-Chinese