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. 2018 Jun 20;12(7):7148–7158. doi: 10.1021/acsnano.8b03023

Figure 3.

Figure 3

Global correlation between 5-hmC profiles produced by optical 5-hmC mapping and hMeDIP-seq. (A) Coverage as a function of distance from TSS. (B) Coverage as a function of distance from H3K4me1 histone modification peaks. (C) Coverage as a function of distance from H3K27Ac histone modification peaks. (D) Comparison of coverage produced by both methods in a representative 500 kbp region from chromosome 1. hMeDIP-seq results are presented in 1 kbp resolution.