Table 1. Model parameters.

Parentheses after the values denote the uncertainty in the last digit.

	Physical interpretation	Value
E0	Free energy barrier to rupture at small α	21.8(2) kBT
E1	Extra free energy barrier to rupture at large α	5.8(2) kBT
H	Free energy barrier for small-to-large α transition	25(2) kBT
G	Free energy offset between angular basins	5(2) kBT
d	Transition state distance	0.56(1) nm
r0	Distance from hinge to FABD-actin interface	1.7(2) nm
αmin	Minimum angle between M2-M3 domains	48°
αc	Transition angle between small and large α wells	53(3)°
αmax	Maximum angle between M2-M3 domains	169(9)°