Figure 3. Effect of pCI-SOCS3 vector or SOCS3 siRNA transfection on DR4 mRNA expression.
mRNA expression levels of DR4, DR5 and SOCS3 were quantified by real-time PCR. DR4 mRNA expression was increased by IFN-α stimulation but not by SOCS3. The y axis shows the relative mRNA expression level. The results are expressed as the relative mean ratio ± SE of at least three independent determinations. *p < 0.05 for two-tailed paired t test compared with control.