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Fig. 2. (a), (b) Temperature–time curves of different solutions under exposure to the 808 nm laser (2 W cm–2) and thermal images of different solutions before (top) and after (bottom) NIR irradiation. (c) The irradiation cycle experiment of SiO2@Au@MnO2–DOX/Apt, every cycle was composed of 5 min irradiation followed by a 5 min cooling phase. (d) Thermal images of the irradiation cycle experiment.