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. 2017 May 10;14(1):22–38. doi: 10.1900/RDS.2017.14.22

Figure 3. Effect of low molecular weight CC-I isomers on islet isolation parameters.

Figure 3

The figure shows the effect of low molecular weight CC-I isomers on islet yield (A), fragmentation index (B), viability (C), and graft function of isolated rat islets transplanted beneath the kidney capsule of diabetic nude mice (D). Islets were isolated utilizing 20 PZ-U of collagenase activity and 0.4 DMC-U of CNP activity. Nephrectomy (Nx) was performed at day 32 post-transplant as indicated. A-C: *p < 0.05, **P < 0.01, as indicated. D: *p < 0.05, **p < 0.01 vs. standard NB-1 and intact CC-I blend.