Table 2. Comparison of the expression of Bcl-2 mRNA in rats’ ovaries (n=10).
| Group | Genistein dose | Semiquantitative scoring of the positive expression of Bcl-2 mRNA | Positive | Positive reactions (%) |
|||
|---|---|---|---|---|---|---|---|
| Negative expression |
Weak positive expression |
Moderate positive expression |
Strong positive expression |
Integral | |||
| CG | 5 | 3 | 1 | 1 | 18 | 50 (5/10) | |
| MG | 7 | 1 | 2 | 0 | 15 | 30 (3/10) | |
| L-Gen | 5 mg/kg bw | 2 | 2 | 2 | 4 | 28 | 80 (8/10) |
| M-Gen | 10 mg/kg bw | 0 | 4 | 2 | 4 | 30 | 100 (10/10) |
| H-Gen | 20 mg/kg bw | 0 | 2 | 3 | 5 | 33a) | 100 (10/10) |
| EG | 0.5 mg/kg bw | 0 | 1 | 1 | 8 | 37a) | 100 (10/10) |
Expression of Bcl-2 mRNA and positive reactions in rats’ ovaries of Wistar rats after 15 days of treatment with genistein. Experimental conditions and treatment procedures are given in materials and methods. a) Significant against model group (P<0.05), ANOVA test.