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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Arthritis Rheumatol. 2018 Aug 6;70(9):1429–1439. doi: 10.1002/art.40521

Figure 3. Frequency of IR-expressing T cells inversely correlated to inflammatory cytokine production and activity of the disease.

Figure 3

A–B, Frequency of cells producing the indicated effector cytokines within peripheral CD8+ (A) and CD4+ (B) T cell gates in HD, rRA and nrRA patients. Mean±DS is shown. C, Correlations between the frequencies of peripheral CD8+ T cells expressing PD-1 and CD160 together, and PD-1 and CD160 individually and DAS28 from RA patients. Datasets include RA patients at the indicated times post-treatment. Statistical analysis: p values calculated with One-way Anova followed by Bonferroni post-test (A and B) and Pearson’s correlation coefficient (C).