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. 2018 Aug 29;8:12998. doi: 10.1038/s41598-018-31171-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Rab14 silencing impairs the internalization of CD36. Macrophages were treated with (a) siRNA control, (b) siRNA for Rab14 or (c) siRNA for Rab9a and the surface levels of CD36 analyzed by flow cytometry. Columns represent the mean fluorescence intensity (MFI) of CD36 determined after different incubation times at 37 °C, using an anti-CD36 antibody. Error bars indicate the standard error of the mean of four independent experiments. Statistical significance (*p < 0.05; **p < 0.01; ***p < 0.001) refers to the difference between the 10, 15 or 30 minutes and 5 minutes incubation.