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. 2018 Aug 29;8:12998. doi: 10.1038/s41598-018-31171-5

Figure 6.

Figure 6

Rab9a silencing impairs the internalization of TLR4. Macrophages were treated with (a) siRNA control, (b) siRNA for Rab9a or (c) siRNA for Rab14 and the surface levels of TLR4 analyzed by flow cytometry. Columns represent the mean fluorescence intensity (MFI) of TLR4 determined after different incubation times at 37 °C, using an anti-TLR4 antibody. Error bars indicate the standard error of the mean of three independent experiments. Statistical significance (*p < 0.05; **p < 0.01) refers to the difference between the 10, 15 or 30 minutes and 5 minutes incubation.