Table 1.
Structural statistics for the solution structures of the 1:1 and 4:2 Pt-tripod–Tel26 complexes
| 1:1 Complex | 4:2 Complex | |
|---|---|---|
| NMR distance and dihedral constraints | ||
| Distance restraints | ||
| Total NOE | 652 | 771 |
| Intra-residue | 287 | 256 |
| Inter-residue | 208 | 262 |
| Sequential (|i – j| = 1) | 148 | 192 |
| Nonsequential (|i – j| > 1) | 60 | 70 |
| Hydrogen bonds | 24 | 30 |
| Pt-tripod (Intramolecular) | 24 | 24 |
| Intermolecular (Pt-tripod/Tel26) | 109 | 199 |
| Total dihedral angle restraints | 14 | 18 |
| Structure statistics | ||
| Violations (mean and s.d.) | ||
| Distance constraints (Å) | 0.033 ± 0.022 | 0.047 ± 0.037 |
| Dihedral angle constraints (°) | 0.765 ± 0.113 | 0.994 ± 0.324 |
| Max. dihedral angle violation (°) | 10.39 | 10.11 |
| Max. distance constraint violation (Å) | 0.430 | 0.564 |
| Deviations from idealized geometry | ||
| Bond lengths (Å) | 0.013 ± 0.012 | 0.019 ± 0.014 |
| Bond angles (°) | 1.530 ± 0.040 | 1.453 ± 0.025 |
| Impropers (°) | 0.985 ± 0.024 | 0.939 ± 0.016 |
| Average pairwise r.m.s. deviationa (Å) | ||
| G-tetrad | 0.55 ± 0.17 | 0.75 ± 0.26 |
| All | 1.33 ± 0.38 | 1.65 ± 0.36 |
aPairwise r.m.s. deviation was calculated among 15 refined structures