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. 2018 Aug 29;9(9):872. doi: 10.1038/s41419-018-0853-x

Fig. 7. Proposed mechanism for the radio-protective effect of α6-integrin in GBM.

Fig. 7

We showed that α6-integrin contributes to GBM radioresistance by: controlling DNA damage checkpoint and repair via CHK1 and Cdc25c and regulating the transcriptional network ZEB1/OLIG2/SOX2