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. 2018 Aug 29;9(9):881. doi: 10.1038/s41419-018-0898-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Immunohistochemistry staining of RASAL2 in normal kidney tissues (n = 18) and RCC tissues (n = 47). The scale bar is 40 µm. b RASAL2 mRNA expression in normal kidney tissues and matched RCC tissues from GEO database (GSE46699 and GSE40435). c Real-time quantitative PCR of RASAL2 mRNA expression in human RCC cell lines. d RASAL2 mRNA expression in human RCC tissues with different stages (T) and grades (g) from TCGA. e Kaplan–Meier analysis (long-rank test) of overall survival of RCC patients with high (n = 266) or low (n = 266) RASAL2 mRNA expression from TCGA. ^**P < 0.01, ^***P < 0.001, ns no significant