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. 2018 Aug 29;8:13037. doi: 10.1038/s41598-018-31353-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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FMT from CR mice attenuated diet-induced obesity and partially ameliorated metabolic disturbances. (A) Schematic design of the FMT experiment. NC, normal chow; HFD, high fat diet. (B) Body weight curves of mice fed HFD (n = 6–8 per group). (C,D) Quantification of body fat mass (C) and lean mass (D) by MRI scans (n = 6–8 per group). (E) Oral glucose tolerance test of mice received FMT (n = 6–8 per group) with area under curve (AUC) shown in the inlet. (F) Representative H&E staining of the liver. Scale bar, 50 μm. (G) Hepatic triglyceride levels of the mice fed HFD (n = 6–8 per group). Data are expressed as means ± s.e.m, *p < 0.05, **p < 0.01.