Table 2.

Conditional logistic regression of biomarker levels (TRD vs. control group; N = 72).

Biomarker	OR	X2	95% Confidence intervals		p
			Lower	Upper
PRE-TREATMENT
Tie2	2.651	11.672	1.325	5.303	0.006*
PlGF	0.344	0.383	0.011	10.386	0.547
VEGF	1.365	0.216	0.366	5.089	0.652
VEGFC	0.159	3.327	0.018	1.362	0.045*
VEGFD	0.118	3.738	0.011	1.220	0.087
bFGF	0.288	2.949	0.124	1.209	0.084
sFlt1	0.377	0.273	0.009	15.098	0.627
BDNF	0.025	11.921	0.001	0.500	0.012*
POST-TREATMENT
Tie2	3.008	11.823	1.308	6.917	0.010*
PlGF	1.326	1.156	0.781	2.251	0.295
VEGF	0.818	0.123	0.266	2.519	0.728
VEGFC	0.083	7.853	0.008	0.839	0.007*
VEGFD	0.128	2.064	0.007	2.475	0.196
bFGF	0.681	0.413	0.209	2.220	0.572
sFlt1	0.201	0.809	0.006	7.007	0.354
BDNF	0.028	5.557	0.001	1.338	0.126

^*Different between patients and controls, at both p < 0.05 and q < 0.1.

OR, odds ratio; x², Chi-square.

Other factors did not differ between patient (n = 36) and control groups (n = 36) following FDR control for multiple comparisons.