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Location and expression of ARG1, ODC1, and SMOX in polycystic kidneys
| Location/Expression | Key Enzymes | ||
|---|---|---|---|
| ARG1 | ODC1 | SMOX | |
| Cellar location | |||
| CLECs | √ | ||
| RTECs | √ | ||
| Mesenchymal cells | √ | √ | √ |
| Subcellular localization | |||
| Cytoplasm | √ | √ | |
| Nuclei | √ | ||
| mRNA expression in kidneys | |||
| P22 PKs versus P22 WTKs | ↑ | ||
| P30 PKs versus P30 WTKs | ↑ | ↑ | |
| P30 PKs versus P22 PKs | ↑ | ↑ | |
√, position where the enzymes were located; ↑, upregulation; PKs, polycystic kidneys; WTKs, WT kidneys.
