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. 2018 Aug 28;3(4):563–572. doi: 10.1016/j.jacbts.2018.01.014

Figure 1.

Figure 1

Proposed Interplay Between Apoptosis and Endothelial Senescence and Its Implications for Pathogenesis

ATM = ataxia telangiectasia mutated; b-FGF = basic fibroblast growth factor; ERK = extracellular signal-regulated kinase; IGF = insulin-like growth factor; LDL = low-density lipoprotein; MAPK = mitogen-activated protein kinase; SASP = senescence-associated secretory phenotype; SEK1 = stress-activated protein kinase 1; TNF = tumor necrosis factor.