Table A2.
Associations between concentrations of human milk adipokines and infant characteristics.
| Predictor (Concentration, ng/mL) | 2 Months | 5 Months | 9 Months | 12 Months | p-Value | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Intercept (SE) | Slope (SE) | Intercept (SE) | Slope (SE) | Intercept (SE) | Slope (SE) | Intercept (SE) | Slope (SE) | Predictor | Infant Age (Months) | Interaction | ||||
| Infant fat-free mass with ultrasound 4 skinfolds (kg) | ||||||||||||||
| Whole milk adiponectin | 4.53 (0.22) a | −0.032 (0.015) | 5.76 (0.21) | −0.032 (0.015) | 6.77 (0.20) | −0.032 (0.015) | 7.58 (0.23) | −0.032 (0.015) | 0.025 b | <0.001 | 0.052 c | |||
| Infant fat-free mass with bioelectrical impedance spectroscopy (kg) | ||||||||||||||
| Whole milk leptin | 4.53 (0.42) | −0.33 (0.76) | 5.49 (0.30) | −0.44 (0.55) | 5.01 (0.57) | 2.64 (0.55) | 5.62 (0.59) | 2.77 (1.04) | 0.24 | <0.001 | 0.016 | |||
| Infant head circumference (cm) | ||||||||||||||
| Skim milk leptin | 40.30 (0.44) | −1.85 (0.84) | 43.30 (0.40) | −1.85 (0.84) | 45.80 (0.39) | −1.85 (0.84) | 46.80 (0.39) | −1.85 (0.84) | 0.028 | <0.001 | 0.37 | |||
a Parameter estimate ± SE; effects of predictors taken from linear mixed effects models that accounted for month after birth and an interaction between month after birth and predictor with a random effect per participant; if the interaction is not significant parameter estimates are taken from a model with no interaction. b,c Results are presented only for interactions or predictors with raw p-values < 0.05; after the false discovery rate adjustment, the interaction/predictor p-values were considered to be significant at <0.025 for whole milk adiponectin concentration (none are significant), at <0.016 for whole milk leptin (none are significant) and at <0.028 for skim milk leptin concentrations (none are significant).