Figure 1.

Complexes and route of protein entry into the mitochondrial compartments. The colored lines depict the routes of protein translocation into the different compartments of the yeast mitochondria (detailed in the “signals targeting precursors to the mitochondrial sub-compartments” section). Known components of the yeast translocation complexes are shown and those for which homologues are found in the genomes of Toxoplasma and Plasmodium spp. are in grey. MIM: mitochondrial import complex; PAM: pre-sequence translocase Associated Motor; SAM: sorting and assembly machinery complex; TOM: translocase of the outer mitochondrial membranes.