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. 2018 Aug 13;10(8):1082. doi: 10.3390/nu10081082

Figure 2.

Figure 2

Inhibitory activity of sitagliptin on DPP-IV activity measured in situ on 2-day Caco-2 cells: (a) at 1 µM, sitagliptin inhibited DPP-IV activity in Caco-2 cells by over 50%; (b) sitagliptin inhibited DPP-IV activity in a dose-response manner, exhibiting an IC50 of 0.6 µM. Data are the means ± SD of three experiments performed in triplicate.