Table 1.
Baseline data (n = 525).
| Variables | All Cases (n = 525) |
HCV Group (n = 440) |
HBV Group (n = 85) |
p Value (HCV vs. HBV) |
|---|---|---|---|---|
| Age (years) | 64.4 (20.8–94.0) | 65.0 (20.8–94.0) | 55.8 (28.8–77.0) | <0.0001 |
| Gender, male/female | 268/257 | 218/222 | 50/35 | 0.1247 |
| Body mass index (kg/m2) | 22.2 (13.1–34.4) | 22.2 (13.1–34.4) | 22.2 (15.9–30.4) | 0.6839 |
| ECW to TBW ratio | 0.387 (0.363–0.433) | 0.388 (0.365–0.433) | 0.381 (0.363–0.425) | <0.0001 |
| Skeletal muscle mass index (cm2/m2) | 6.56 (3.50–10.21) | 6.51 (3.50–10.21) | 6.92 (5.21–9.90) | 0.0099 |
| Liver histology (F0-1, F2, F3, Child-Pugh A/B/C) | 106/53/64/226/72/4 | 79/41/56/198/62/4 | 27/12/8/28/10/0 | 0.0394 |
| Total bilirubin (mg/dL) | 0.9 (0.2–5.1) | 0.9 (0.2–5.1) | 0.9 (0.3–2.8) | 0.5264 |
| Serum albumin (g/dL) | 3.9 (2.3–5.1) | 3.9 (2.3–5.1) | 4.0 (2.7–5.1) | 0.0017 |
| Prothrombin time (%) | 87.0 (39.2–130.3) | 86.4 (39.2–130.3) | 89.6 (43.3–123.0) | 0.2371 |
| Platelet count (× 104/mm3) | 12.8 (2.6–48.1) | 12.4 (3.0–48.1) | 14.9 (2.6–37.9) | 0.0022 |
| Serum creatinine (mg/dL) | 0.68 (0.30–7.69) | 0.67 (0.30–7.69) | 0.75 (0.46–6.0) | 0.0021 |
| Total cholesterol (mg/dL) | 156 (73–293) | 153 (73–293) | 171 (82–293) | 0.0100 |
| Triglyceride (mg/dL) | 85 (25–554) | 85 (25–554) | 85 (30–256) | 0.5929 |
| AST (IU/L) | 38 (10–756) | 40 (10–349) | 30 (13–756) | <0.0001 |
| ALT (IU/L) | 33 (7–1079) | 34 (7–258) | 29 (7–1979) | 0.0304 |
| BTR | 4.95 (1.65–19.68) | 4.77 (1.65–19.68) | 5.85 (1.82–11.28) | 0.0002 |
| FIB-4 index | 3.56 (0.22–20.04) | 3.80 (0.22–20.04) | 1.95 (0.37–19.14) | <0.0001 |
| Fasting blood glucose (mg/dL) | 99 (64–403) | 100 (64–403) | 95 (70–283) | 0.1764 |
Data are expressed as number or median (range). HBV: hepatitis B virus; HCV: hepatitis C virus; ECW: extracellular water; TBW: total body water; AST: aspartate aminotransferase; ALT: alanine aminotransferase; BTR: branched-chain amino acid to tyrosine ratio.