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Fig. 3. Heatmap of the top 100 most significantly altered miRNAs (p ≤ 0.05) within the three testicular cell lines (A) GC1 spermatogonia, and (B) TM3 Leydig and (C) TM4 Sertoli cells following treatment with DOX. Expression levels represent log2[DOX/control] (Log2R) or fold change[DOX/control] (FC), with downregulations shown in green and upregulations in red.