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. 2018 Aug 16;10(8):273. doi: 10.3390/cancers10080273

Table 4.

Common transcription factors of PEBP1 and interacting genes.

Factor Name Function
ERCC6 ERCC Excision Repair 6, Chromatin Remodeling Factor A DNA-binding protein that is important in transcription-coupled excision repair. Several polymorphisms the gene coding region were associated with susceptibility to development of cancer and chemoresistancy [22,23].
VEZF1 Vascular Endothelial Zinc Finger 1 A transcriptional regulatory protein that is involved in angiogenesis. Contribute to the epigenetic aberrations and the associated tumorigenesis [24,25].
hsa-miR-378c Close relative (hsa-miR-378a) Inhibits cell growth and enhances apoptosis in cancer [26].
hsa-miR-761 Enhances cancer growth, migration and invasion [27].
hsa-miR-23c Close relative (hsa-miR-23a) Associated with autophagy, loss of RKIP/PEBP1 and multiple tumors [28,29].