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. 2018 Aug 1;9(8):392. doi: 10.3390/genes9080392

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Coverage of different genomic contexts by input alignments and high-confidence loci, respectively. High-confidence loci are slightly depleted in genic vs intergenic regions and in exonic vs intronic regions. They are strongly enriched (1.6-fold) in noncoding exons, which, in turn, is due to the enrichment in the 3’-untranslated regions (3’-UTRs) (1.7-fold) of messenger RNAs (mRNAs). Short non-coding RNAs (sncRNA) contain the classic highly structured small RNAs, such as microRNAs and small nucleolar (snoRNAs), and are strongly enriched compared to long non-coding RNAs (lncRNA). CDS: Coding sequences.