Figure 11.

Acute and chronic effects of treatment on deoxygenated haemoglobin concentrations. Mean (±SEM) deoxygenated haemoglobin concentrations during 5 min of rest (averaged into 2 ×2.5 min epochs) and 30 min (three repetitions) of the cognitive demand battery (CDB). Each 10 min CDB comprises 1 × 2 min epoch of serial 3 and 1 × 2 min epoch of serial 7 subtractions and 2 × 2.5 min epochs of Rapid Visual Information Processing (RVIP). (left) Deoxygenated haemoglobin changes on Day 1; and (right) deoxygenated haemoglobin changes following 28 days of supplementation with 475 mg Sideritis scardica (SS), 950 mg SS, active control (240 mg Ginkgo biloba) or placebo control. Data on both days were recorded during a ~150–240 min post-dose period and converted from the pre-dose baseline on Day 1. * = p < 0.05.