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. 2018 Aug 29;10:1758835918794628. doi: 10.1177/1758835918794628

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© The Author(s), 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Characteristics of the Cancer Genome Atlas (TCGA) Research Network and the Asian Cancer Research Group (ACRG) gastric cancer cohorts. A summary with the different proposed subtypes is presented for each cohort. (a) TCGA subtypes: MSI: tumors with microsatellite instability; EBV+: tumors positive for Epstein-Barr virus; GS: genomically stable tumors; CIN: tumors with chromosome instability. (b) ACRG subtypes: MSI: tumors with microsatellite instability; MSS/TP53+: stable tumors with active TP53; MSS/TP53–: stable tumors with inactive TP53, MSS/EMT: stable tumors expressing an EMT signature. The clinical characteristics and main genetic and molecular alterations are listed for each subtype.