Table 1.
Results from the initial screening of essential oils (receptor binding at a concentration of 0.1 mg/mL) and major constituents detected in each Mentha species by GC-MS analysis.
| Mentha spicata | Mentha × piperita | |||||
| Essential Oil Number | 1 | 2 | 3 | 4 | 5 | 6 |
| GABAA receptor % displacement (3H) flunitrazepam |
35 ± 3 | 25 ± 2 | 42 ± 5 | 42 ± 3 | 25 ± 2 | 15 ±2 |
| Nicotinic receptor % displacement (3H) nicotine |
30 ± 3 | 25 ± 4 | 21 ± 8 | 52 ± 5 | 50 ± 5 | 49 ± 1 |
| NMDA receptor % displacement (3H) MK801 |
0 ± 3 | 0 ± 2 | 5 ± 4 | 0 ± 2 | 10 ± 3 | 5 ± 1 |
| AChE Inhibition % | 79.45 | 66.21 | 70.78 | 70.09 | 73.97 | 73.74 |
| Major constituents detected in each sample by GC-MS | ||||||
| % Limonene | 20.8 | 20.8 | 18.4 | 2.3 | 2.4 | 2.0 |
| % Carvone | 61.9 | 57.5 | 58.8 | 0.1 | 0.1 | 0.1 |
| % Menthone | 0.4 | 1.7 | 0.1 | 24.9 | 24.7 | 24.2 |
| % Menthol | 0.5 | 2.8 | 0.80 | 36.7 | 32.5 | 34.7 |