Table 1.
ICD-9 CM and generic product index codes.
| Variable | Code specification |
|---|---|
| Lactic acidosis risk factors | |
| Chronic obstructive pulmonary disease | ICD-9 code: 490.x-496.x |
| Hepatic dysfunction | ICD-9 code: 571.2, 571.4-571.6, 572.2-572.8 |
| Alcohol abuse | ICD-9 code: 305.0 |
| Heart failure | ICD-9 code: 428.x |
| Renal insufficiency | ICD-9 code: 582.x, 585.x |
| History of acidosis event | ICD-9 code 276.2x on a hospital discharge claim prior to the index diagnosis |
| Medication use | |
| Sulfonylurea | GPI: 272000 |
| Glucagon-like peptide-1 agonist | GPI: 271700 |
| Thiazolidinedione | GPI: 276070 |
| Dipeptidyl peptidase-IV inhibitor | GPI: 275500 |
| Insulin | GPI4: 2710 |
| Metformin | GPI6: 272500 |