Table 4.
First Author, Year | Amino Acids | Carbohydrates | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Histidine | Serine | Trigonelline | Tyrosine | Acetone | Cytidine | Methyladenosine | Methanol | 2,2,-Methylguanosine | Pseudouridine | |
Nakajima, 2018 [47] | ||||||||||
Deng, Chang, 2017 [48] | ||||||||||
Deng, Fang, 2017 [19] | → | ↓ | → | → | → | → | ||||
Wang, 2017 [49] | ||||||||||
Rozalski, 2015 [50] | ||||||||||
Wang, 2014 [51] | → | ↓ | → | → | → | → | ||||
Eisner, 2013 [16] | ↑ | ↑ | ↓ | ↓ | ||||||
Hsu, 2013 [52] | ↑ | ↑ | ||||||||
Yue, 2013 [17] | ||||||||||
Chen, 2012 [53] | ↓ | ↓ | ||||||||
Cheng, 2012 [54] | ||||||||||
Wang, 2010 [21] | ↑ | ↑ | ↑ | ↑ | ||||||
Johnson, 2006 [20] | ||||||||||
Feng, 2005 [55] | ↑ | |||||||||
Hiramatsu, 2005 [56] | ||||||||||
Zheng, 2005 [57] | ↑ | ↑ | ↑ | ↑ |
Abbreviations: ↑, increased levels in cases compared to healthy individuals; ↓, decreased levels in cases compared to healthy individuals; →, significant differences between cases and healthy individuals (not reported if increased or decreased). Empty lines indicate that this specific metabolite was not investigated in the corresponding study.