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. 2018 Aug 9;10(8):418. doi: 10.3390/v10080418

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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ERVs related to the AKR6 substitutions map to chromosomal regions that originated in Asian mice. (a) Horizontal tracks represent a 10-Mb segment of chromosome 11 in selected strains and subspecies typed for Xmv67. Chromosomal regions originating from M. m. domesticus are in blue and M. m. musculus in red. PCR typing is shown on the right. The position of the AKR ERV insertion site at Chr11:97 (based on NCBI37/mm9) is marked by an inverted triangle. (b) Polymorphic SNPs surrounding the Xmv67 insertion site are shown for a subset of the tested mice. Yellow highlights the AKR-specific SNPs. (c) Distribution of Xmv67 in subspecies of M. musculus.