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. 2018 Jul 27;10(8):982. doi: 10.3390/nu10080982

Figure 5.

Figure 5

Effects of lower doses of menaquinone-4 on the expression of genes involved in bile acid synthesis and energy homeostasis. Menaquinone-4 (MK-4; 10 or 50 mg/kg BW) was given by oral gavage to wild-type (WT) and hPXR female mice. After 6 h, mRNA levels of genes regulating bile acid synthesis (A) and energy homeostasis (B) were measured by quantitative RT-PCR. The relative mRNA levels were normalized to the amount of eukaryotic translation elongation factor 1α1 mRNA. Data are expressed as the mean ± SEM, n = 4. $ p < 0.01, * p < 0.05, compared to control.