Table 2.
Groups | Body Weight (g) | Liver Weight (g) | Ratio (Liver/Body Weight) | |
---|---|---|---|---|
Wild type | Control | 19.7 ± 0.440 * | 0.740 ± 0.0386 | 0.0375 ± 0.00160 |
10 mg/kg BW | 20.1 ± 0.614 | 0.7875± 0.0175 | 0.0392 ± 0.00072 | |
50 mg/kg BW | 20.6 ± 0.795 | 0.770 ± 0.0409 | 0.0377 ± 0.00169 | |
100 mg/kg BW | 19.4 ± 0.290 | 0.807 ± 0.0169 | 0.0417 ± 0.00030 | |
hPXR | Control | 18.0 ± 0.422 | 0.776 ± 0.0281 | 0.0436 ± 0.0025 |
10 mg/kg BW | 17.3 ± 0.414 | 0.798 ± 0.0253 | 0.0461 ± 0.00081 | |
50 mg/kg BW | 17.4 ± 0.232 | 0.808 ± 0.0317 | 0.0465 ± 0.00218 | |
100 mg/kg BW | 18.7 ± 0.396 | 0.822 ± 0.0348 | 0.0439 ± 0.00091 |
* Data are expressed as the mean ± SEM, n = 4–9.