Table 3.

Comparison of fold changes of gene expression levels (compared to corresponding control) in wild-type and hPXR mice.

Function	Gene Symbol	WT MK-4 *	hPXR MK-4	hPXR Rif
Bile homeostasis	Cyp7a1	2.24	0.07	0.39
	Cyp8b1	1.11	0.45	0.99
	Cyp39a1	0.93	1.82	1.12
	Nceh1	0.97	1.83	1.91
Energy homeostasis	Aldoc	1.44	0.44	0.73
	Lipin1	1.03	2.00	0.75
	Pdk4	0.61	2.12	0.96
	Slc2a5	0.99	0.51	0.71

* WT, wild type; MK-4, menaquinone-4; Rif, rifampicin.