Table 3.
Function | Gene Symbol | WT MK-4 * | hPXR MK-4 | hPXR Rif |
---|---|---|---|---|
Bile homeostasis | Cyp7a1 | 2.24 | 0.07 | 0.39 |
Cyp8b1 | 1.11 | 0.45 | 0.99 | |
Cyp39a1 | 0.93 | 1.82 | 1.12 | |
Nceh1 | 0.97 | 1.83 | 1.91 | |
Energy homeostasis | Aldoc | 1.44 | 0.44 | 0.73 |
Lipin1 | 1.03 | 2.00 | 0.75 | |
Pdk4 | 0.61 | 2.12 | 0.96 | |
Slc2a5 | 0.99 | 0.51 | 0.71 |
* WT, wild type; MK-4, menaquinone-4; Rif, rifampicin.