Figure 2. FIGURE 2: Phosphoproteome dynamics during mitotic exit controlled by kinases.

Scheme summarizing how kinases impact on both protein phosphorylation and dephosphorylation during mitotic exit. Phosphosites carrying Polo-like kinase consensus motifs are phosphorylated early during mitotic exit, followed by Aurora and NDR family kinases and finally casein kinase II (CKII) consensus motifs. In turn, phosphosites displaying a full Cdk consensus motif are dephosphorylated first, followed by minimal Cdk motifs and finally Polo-like kinase motifs.