Table 1.
Clinicopathological characteristics of the 445 enrolled female RCC patients.
| Case |
Control |
P value | ||
|---|---|---|---|---|
| (n = 445) | (n = 508) | |||
| Age | 0.928 | |||
| (mean ± SD) | 53.4 ± 12.1 | 52.3 ± 12.5 | ||
| BMI | 0.020 | |||
| (n, %) | <25 | 270 (60.67) | 345 (67.91) | |
| ≥25 | 175 (39.33) | 163 (32.09) | ||
| Hypertension | 0.036 | |||
| (n, %) | yes | 169 (37.98) | 160 (31.50) | |
| no | 276 (62.02) | 348 (68.50) | ||
| Diabetes | <0.001 | |||
| (n, %) | yes | 131 (29.44) | 85 (16.73) | |
| no | 314 (70.56) | 423 (83.27) | ||
| Menopause | 0.820 | |||
| (n, %) | yes | 280 (62.92) | 316 (62.20) | |
| no | 165 (37.08) | 192 (37.80) | ||
| Use of HRT | 0.290 | |||
| (n, %) | yes | 28 (6.29) | 41 (8.07) | |
| no | 417 (93.71) | 467 (91.93) | ||
| WC | <0.001 | |||
| (n, %) | quartile1 | 94 (21.12) | 144 (28.35) | |
| quartile2 | 94 (21.12) | 143 (28.15) | ||
| quartile3 | 130 (29.21) | 111 (21.85) | ||
| quartile4 | 127 (28.54) | 110 (21.65) | ||
| Fuhrman grade | ||||
| (n, %) | I | 22 (4.94) | / | |
| II | 201 (45.17) | / | ||
| III | 128 (28.76) | / | ||
| IV | 23 (5.17) | / | ||
| missing | 71 (15.96) | / | ||
| Stage at diagnosis | ||||
| (n, %) | I | 352 (79.10) | / | |
| II | 55 (12.36) | / | ||
| III | 13 (2.92) | / | ||
| IV | 25 (5.62) | / | ||
| Pathological type | ||||
| (n, %) | ccRCC | 364 (81.80) | / | |
| papillary RCC | 18 (4.04) | / | ||
| chromophobe RCC | 40 (8.99) | / | ||
| other | 23 (5.17) | / |
BMI: Body Mass Index; WC: Waist Circumference; HRT: hormone replacement therapy; RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma.