Table 6.

Associations between maternal untransmitted alleles and candidate lipid species’ peak intensity

SNP	Gene	Lipid	Discovery Cohort			Validation Cohort			Meta-Analysis
			R	p-value	n	R	p-value	n	R	p-value
rs10839220	KRTAP5–6	TG(44:1)	0.113	0.16	154	0.067	0.38	179	0.09 (−0.02, 0.19)	0.05
rs10839220	KRTAP5–6	LysoPCP(18:0)	0.095	0.24	154	0.114	0.10	213	0.11 (0, 0.21)	0.02
rs10839220	KRTAP5–6	PE(34:0)	0.068	0.54	154	0.042	0.40	213	0.05 (−0.05, 0.15)	0.16
rs10839220	KRTAP5–6	DG(36:3)	0.122	0.13	154	0	0.98	190	0.06 (−0.06, 0.17)	0.18
rs4752779	FAM99B	TG(44:1)	0.020	0.81	161	0.054	0.47	185	0.04 (−0.07, 0.14)	0.24
rs7131362	FAM99A	TG(44:1)	0.119	0.14	153	0.050	0.51	175	0.08 (−0.03, 0.19)	0.07
rs7131362	FAM99A	TG(48:0)	0.080	0.43	153	0.065	0.26	198	0.07 (−0.03, 0.18)	0.09
rs17073273	PLAGL1	TG(44:1)	0.131	0.09	170	0.024	0.74	201	0.07 (−0.03, 0.18)	0.09
rs17073273	PLAGL1	TG(55:9)	0	0.98	170	0.123	0.06	228	0.07 (−0.05, 0.19)	0.13
rs17073273	PLAGL1	TG(48:0)	0.094	0.22	170	0.067	0.31	228	0.08 (−0.02, 0.18)	0.06
rs2268445	PLAGL1	TG(44:1)	0.092	0.23	172	0.022	0.76	201	0.05 (−0.05, 0.16)	0.15

Only those lipid species that tagged components with significant fitted models in Metaboanalyst using maternally-transmitted fetal variants are shown