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. 2018 Jul 27;34:139–157. doi: 10.1016/j.ebiom.2018.07.027

Fig. 4.

Fig. 4

Domain-swapping analyses of MCR-3 and its two paralogues (MCR-1 plus EptA).

A. Scheme for domain-swapped constructs between MCR-3 and MCR-1 (or EptA).

B. Western blot analyses for the expression of mcr-3 and its mosaic versions in E. coli.

C. Measurement of colistin MIC of E. coli strains carrying mcr-3 and its hybrid derivatives.