Fig. S8.

Structural similarity of PE-recognizing cavities of MCR-like enzymes.

A. A putative Zn2+-centering, five-residues forming motif is conserved amongst PE lipid substrate-recognizing cavities of four MCR-like paralogues EptA, MCR-1, MCR-2 and MCR-3. B. Comparative analyses of the conserved PE-recognizable residues of four MCR-like enzymes EptA, MCR-1, MCR-2 and MCR-3 With an exception that the conserved serine (S325 in EptA, S330 in MCR-1 and S328 in MCR-2) is replaced with glycine on the residue 322 (G322) in MCR-3, all the other six residues are identical in these cavities. The photographs are produced with PyMol.