Table 1.
Description of the study population among colorectal cancer patients according to tumor OGN expression level.
| Variables, n (%) | OGN |
P value | ||
|---|---|---|---|---|
| Low(n = 130) | Intermediate(n = 105) | High(n = 41) | ||
| Gender | ||||
| Male | 81(62.3) | 48(45.7) | 13(31.7) | 0.885 |
| Female | 49(37.7) | 57(54.3) | 28(68.3) | |
| Age, years | 56.73 ± 10.887 | 57.86 ± 11.741 | 56.83 ± 9.620 | 0.723 |
| T stage | 0.114 | |||
| T2 | 18(13.8) | 19(18.1) | 6(14.6) | |
| T3 | 22(16.9) | 17(16.2) | 15(36.6) | |
| T4 | 90(69.2) | 69(65.7) | 20(48.8) | |
| TNM stage | 0.584 | |||
| I | 10(7.7) | 8(7.6) | 3(7.3) | |
| II | 42(32.3) | 24(22.9) | 15(36.6) | |
| III | 52(40.0) | 61(58.1) | 19(46.3) | |
| IV | 26(20.0) | 12(11.4) | 4(9.8) | |
| N stage | 0.8 | |||
| N0 | 62(47.7) | 38(36.2) | 20(48.8) | |
| N1 | 32(24.6) | 35(33.3) | 15(36.6) | |
| N2 | 36(27.7) | 31(29.5) | 6(14.6) | |
| N3 | 0(0) | 1(1.0) | 0(0) | |
| M stage | 0.1 | |||
| M0 | 104(80.0) | 93(88.6) | 37(90.2) | |
| M1 | 26(20.0) | 12(11.4) | 4(9.8) | |
| Grade | 0.597 | |||
| Well/ moderate | 95(73.1) | 77(73.3) | 32(78.0) | |
| Poor | 28(21.5) | 21(20.0) | 7(17.1) | |
| Histological type | 0.846 | |||
| Adenocarcinoma | 122(93.8) | 101(96.2) | 38(92.7) | |
| Mucinous | 8(6.2) | 4(3.8) | 3(7.3) | |
| Lymph node examined | 0.937 | |||
| Median | 14.8 ± 6 | 15.1 ± 6 | 15 ± 5 | |
| Tumor location | 0.269 | |||
| Colon | 54(1.5) | 56(53.3) | 19(46.3) | |
| Rectum | 76(8.5) | 49(6.7) | 22(53.7) | |
| Perineural invasion | 0.31 | |||
| Negative | 109(83.8) | 83(79.0) | 39(95.1) | |
| Positive | 21(16.2) | 22(21.0) | 2(4.9) | |
| Vascular invasion | 0.235 | |||
| Negative | 87(66.9) | 68(64.8) | 33(80.5) | |
| Positive | 43(33.1) | 37(35.2) | 8(19.5) | |
| Adjuvant Chemotherapy | 0.177 | |||
| No | 25(19.2) | 17(16.2) | 7(17.1) | |
| Yes | 82(63.1) | 79(75.2) | 28(68.3) | |
| MS /MMR status | 0.697 | |||
| MSS/MMR-proficient | 87(66.9) | 61(58.1) | 28(68.3) | |
| MSI/MMR-deficient | 43(33.1) | 44(41.9) | 13(31.7) | |
| CEA status | 0.125 | |||
| Normal | 71(54.6) | 70(66.7) | 29(70.7) | |
| Elevated | 53(40.8) | 31(29.5) | 11(26.8) | |
MMR indicates mismatch repair; MS, microsatellite; MSS, microsatellite stability; MSI, microsatellite instability.