Table 2.
Distribution of colorectal cancers according to tumor OGN expression level and the T cells expression score.
| Variables | OGN level |
P value | ||
|---|---|---|---|---|
| Low | Intermediate | High | ||
| CD3+ cell density | 0.74 | |||
| 1 (lowest) | 34(26.2) | 21(20.0) | 6(14.6) | |
| 2 | 49(37.7) | 43(41.0) | 17(41.5) | |
| 3 | 26(20.0) | 26(24.8) | 11(26.8) | |
| 4 (highest) | 21(16.2) | 15(14.3) | 7(17.1) | |
| FOXP3+ cell density | 0.774 | |||
| 1 (lowest) | 45(34.6) | 33(31.4) | 9(22.0) | |
| 2 | 51(39.2) | 41(39.0) | 17(41.5) | |
| 3 | 13(10.0) | 14(13.3) | 7(17.1) | |
| 4 (highest) | 21(16.2) | 17(16.2) | 8(19.5) | |
| PTPRC cell density | 0.078 | |||
| 1 (lowest) | 35(26.9) | 31(29.50) | 17(41.5) | |
| 2 | 50(38.50) | 28(26.7) | 10(24.4) | |
| 3 | 24(18.5) | 34(32.4) | 9(22.0) | |
| 4 (highest) | 21(16.2) | 12(11.4) | 5(12.2) | |
| CD8+ cell density | <0.001 | |||
| 1 (lowest) | 45(34.6) | 51(39.2) | 0(0.0) | |
| 2 | 51(39.2) | 17(16.2) | 2(4.9) | |
| 3 | 16(12.3) | 19(18.1) | 26(63.4) | |
| 4 (highest) | 18(13.8) | 41(39.0) | 13(31.7) | |
P value was calculated by Pearson Chi-Square test between the tumor OGN expression score (ranging from Low to High) and the level of CD3+, CD8+, PTPRC, or FOXP3+ T cells (immunoreactivity score; as continuous variables).