Fig. 2.

Quercetin reduces the spontaneous GABAergic inhibitory postsynaptic current in prefrontal cortical slices. (A) Representative traces showing voltage responses of neurons in layer II–III of prefrontal cortex to 500-ms injection of the current of +200 pA. (B) Representative traces showing GABAergic sIPSCs in the absence (Ctrl, black) or presence (+quercetin, blue) of 100 μM quercetin. (C–G) Summary data showing the amplitude (C), frequency (D), kinetics (E–G) of GABAergic sIPSCs in the absence or presence of 100 μM quercetin. Data are means ± S.E.M. n = 11 cells from 7 mice. N.S., not significant difference; ^⁎p < .05, ^⁎⁎p < .01, paired Student's t-test. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)