Table 2.
Baseline characteristics and comorbidities among participants in MPP stratified by sex and SU levels
| SU at baseline (μmol/L) (n of persons) | Age at baseline (years) | BMI (kg/m2) | Systolic blood pressure (pts not treated for hypertension # (mmHg) | eGFR (ml/min/1.73m2) | s-cholesterol (mmol/L) | s-triglycerides (mmol/L) | Hypertension n (%) | Sibling with hypertension; n (%) | CVD n (%) |
DM n (%) |
Kidney stone attacks ever; n (%) | Mm-MAST ≥ 2*§; n (%) | ESR (mm/h) | Smoking at baseline (n, %) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Men n = 22,433 |
Men with available SU at baseline | ||||||||||||||
| ≤360 n = 16,824 |
43.6 (6.5) | 24.2 (3.1) | 129 (15.5) | 80.0 (10.3) | 5.6 (1.1) | 1.4 (0.8) | 2287 (13.6) | 739 (4.4) | 306 (1.8) | 398 (2.4) | 1461 (8.7) | 4858 (28.9) | 5.7 (6.0) | 8688 (51.6) | |
| 361–405 n = 3353 |
43.8 (6.6) | 25.7 (3.3) | 132 (16.2) | 77.0 (10.5) | 5.7 (1.2) | 1.7(1.2) | 712 (21.2) | 181 (5.4) | 83 (2.5) | 90 (2.7) | 305 (9.1) | 1181(35.2) | 5.7 (5.4) | 1463 (43.6) | |
| > 405 n = 2191 |
44.5 (7.0) | 26.9 (3.7) | 134(16.6) | 75.7 (11.0 | 5.8 (1.1) | 2.1 (1.8) | 662 (30.2) | 177 (8.1) | 84 (3.8) | 86 (3.9) | 203 (10.6) | 867 (39.6) | 6.4 (6.6) | 861 (39.3) | |
| Women n = 10,902 | Women with available SU at baseline | ||||||||||||||
| ≤360 n = 10,357 |
49.5 (7.5) | 24.2 (4.0) | 126 (17.6) | 75.9 (10.8) | 5.8 (1.1) | 1.1 (0.5) | 2130 (20.6) | 1323 (12.8) | 326 (3.1) | 209 (2) | 675 (6.5) | 299 (2.9) | 9.7 (7.5) | 3636 (35.1) | |
| 361–405 n = 327 |
53 (4.8) | 29.0 (5.6) | 136 (20.0) | 70.2 (10.1) | 6.4 (1.1) | 1.7 (0.4) | 173 (52.9) | 56 (17.1) | 23 (7.0) | 27 (8.3) | 33 (10.1) | ** | 13.4 (9.8) | 105 (32.1) | |
| > 405 n = 164 |
53.1(4.6) | 29.3 (5.3) | 137 (18.2) | 67.9 (14.6) | 6.4 (1.1) | 1.9 (1.1) | 81 (49.4) | 33 (20.1) | 15 (9.1) | 16 (9.8) | 15 (9.1) | ** | 14.5(9.3) | 53 (32.3) | |
*Mm-MAST = Malmö modified brief Michigan Alcohol Screening Test
**Calculations were not performed due to few observations
#Number of subjects with missing information were in different groups of SU were in men 13/2/2 and in women 434/11/5
§Number of subjects with missing information were in different groups of SU were in men 2521/314/201
MPP Malmö Preventive Project, SU serum urate, BMI body mass index, eGFR estimated glomerular filtration rate, CVD cardiovascular disease, DM diabetes mellitus, Mm-MAST Malmö-modified brief Michigan Alcohol Screening Test, ESR erythrocyte sedimentation rate