Table 3.

Some compounds inhibitory activity against telomerase.^a

Compound	IC50 (µM)	Compound	IC50 (µM)
1	2.41 ± 0.51	46	1.12 ± 0.27
5	0.71 ± 0.28	47	2.13 ± 0.60
6	2.98 ± 0.59	48	40.15 ± 1.30
7	3.02 ± 0.44	55	47.22 ± 1.52
8	4.33 ± 0.77	56	3.20 ± 0.55
		57	0.97 ± 0.12
12	2.77 ± 0.58	58	39.88 ± 1.29
13	38.99 ± 1.29	59	44.21 ± 2.26
15	1.87 ± 0.41	62	39.89 ± 1.40
17	10.08 ± 1.13	63	45.33 ± 1.87
18	1.09 ± 0.11	67	1.87 ± 0.47
20	4.17 ± 0.39	69	4.22 ± 0.71
22	2.25 ± 0.30	70	1.01 ± 0.13
25	no	71	6.08 ± 1.30
31	0.81 ± 0.07	75	4.40 ± 2.00
36	1.44 ± 0.22	80	49.27 ± 2.55
39	48.76 ± 2.22	81	2.55 ± 0.40
42	no	82	37.88 ± 2.19
44	15.22 ± 1.56
Staurosporineb	8.67 ± 0.18	Staurosporineb	8.67 ± 0.18

^aTelomerase supercoiling activity.

^bStaurosporine is reported as a control.