Table 2.
Study | Year of publication |
Type of study |
Number of participants* |
Male (%) | Mean age |
Patients | Location of study |
Scope | Conflict of interest | Financing | Classification of the duration of the study**** | Total score in Newcastle–Ottawa Scale |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abali et al. 29 | 2014 | Cohort no (concurrent) | 117 (85/32) |
55 | 12 ± 3.4 | Pediatric | Turkey | SC | NR | NR | Long | 7 |
Haukka et al. 30 | 2013 | Cohort no (concurrent) | 7110 (3359/7110) | NR | NR | Pediatric and adult | Finland | MC | Yes | Novo Nordisk | Long | 6 |
Kabadi et al. 31 | 2008 | Cohort no (concurrent) | 45 (24/21) |
56 | NR | Adult | USA | SC | No | No | Intermediate | 7 |
Jinno et al. 32 | 2012 | Cohort no concurrent | 90 (29/90) |
36 | 11.9 ± 3.8 | Pediatric | Japan | MC | NR | Japan Diabetes Foundation | Long | 6 |
Hermansen et al. 33 | 2009 | Cohort no (concurrent) | 643 (643/643) |
39 | 40.3 ±15.7 | Adult | 6 countries ** | MC | Yes | Novo Nordisk | Intermediate | 7 |
Preumont et al. 34 | 2009 | Cohort no (concurrent) | 181 (181/181) |
NR | NR | Adult | Belgium | SC | Yes | Novo Nordisk | Intermediate | 6 |
Yenigun et al. 35 | 2009 | Cohort no (concurrent) |
508 (482/26) |
48 | NR | Adult | 11 countries *** | MC | Yes | Novo Nordisk | Long | 7 |
Dornhorst et al. 36 | 2007 | Cohort no (concurrent) | 3330 (1665/1665) | NR | NR | Adult | Austria, Czech Republic and Denmark | MC | Yes | Novo Nordisk | Short | 5 |
The value in brackets indicates (ni/nc) where, ni = the number of participants in the intervention group (glargine), and nc = the number of participants in the control group (detemir).
Czech Republic, United Kingdom, Republic of Ireland, Netherlands, Sweden and Finland.
Austria, Czech Republic, Denmark, Finland, Germany, Ireland, Israel, Netherlands, Sweden, Turkey and United Kingdom.
Studies with follow-up time up to 3 months were classified as short, 3–6 months as intermediate and >6 months as long.
NR, not reported; Cohort no, study with declaration of no conflict of interest; SC, single center; MC, multicenter.