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. Author manuscript; available in PMC: 2018 Aug 30.
Published in final edited form as: Endocrinology. 2008 Aug 14;149(11):5335–5344. doi: 10.1210/en.2008-0424

Figure 2. The stimulatory effect of estradiol is mediated by an intracellular receptor and does not involve GPR30.

Figure 2

A,B Representative examples of GnRH neurons responding to 15min exposure to 100pM (A) or 100nM (B) E2. C Representative example of a GnRH neuron responding to 5 min exposure to 100nM E2. D,E Representative traces of GnRH neurons that did not respond to 100 nM E2-6-BSA (D) 100 nM 17α-estradiol (E) or 100nM G-1 (F). All of these three cells responded to a caffeine (caf) stimulus at the end of the experiment.