Skip to main content
. 2018 Aug 30;13(8):e0202546. doi: 10.1371/journal.pone.0202546

Table 4. Comparison of frequently prescribed drugs.

Drug Group (ATC 3rd level) F45-Patients Non-F45-Patients F45- vs. Non-F45-Patients
Rank n(%) Rank n(%) Adjusted Odds Ratio
95%-CI; p-value
Non-steroidal anti-inflammatory drugs (painkiller for orthopaedic disorders, antirheumatic agents) 1 8,117 (10.45) 1 68,881 (13.43) 0.967
[0.943, 0.992]; p = 0.0098
Analgesics and antipyretics (painkiller, drugs for fever) 2 6,728 (8.66) 2 42,225 (8.23) 1.018
[0.991, 1.046]; p: n. s.
Opioids (e.g. morphine) 5 3,297 (4.25) 14 9,909 (1.93) 1.625
[1.561, 1.693]; p<0.0001
Antidepressants (e.g. Amitriptyline, Citalopram) 11 1,824 (2.35) 25 4,180 (0.82) 2.014
[1.904, 2.130]; p<0.0001
Hypnotics and Sedatives (Sleep-inducing drugs) 12 1,496 (1.93) 38 3,224 (0.63) 2.160
[2.029, 2.298]; p<0.0001
Anxiolytics (drugs for anxiety disorders) 17 1,236 (1.59) 40 3,144 (0.61) 1.892
[1.769, 2.022]; p<0.0001